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CNE Article

Extremity Cooling: A Synthesis of Cryotherapy Interventions to Reduce Peripheral Neuropathy and Nail Changes From Taxane-Based Chemotherapy

Lauren Peyton
Erica Fischer-Cartlidge
CJON 2019, 23(5), 522-528 DOI: 10.1188/19.CJON.522-528
Background: Taxane-based chemotherapies are frequently used to treat solid tumor cancers. Two significant side effects include nail changes and/or peripheral neuropathy. These side effects can cause pain, infections, dose reductions, and treatment delays, all of which negatively affect quality of...
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Article

Taxane-Induced Peripheral Neuropathy: Objective and Subjective Comparison Between Paclitaxel and Docetaxel in Patients With Breast Cancer

Ya-Ning Chan
You-Wun Jheng
Pei-Ju Wang
Chin-Yau Chen
Ming-Wei Lin
Ya-Jung Wang
CJON 2019, 23(5), 494-501 DOI: 10.1188/19.CJON.494-501
Background: Taxane-induced peripheral neuropathy (TIPN) is caused by the neurotoxicity of paclitaxel and docetaxel, but the differences between paclitaxel- and docetaxel-induced peripheral neuropathy are understudied. Objectives: The purpose of this study is to compare TIPN between docetaxel and...
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CNE Article

Chemobrain: A Pilot Study Exploring the Severity and Onset of Chemotherapy-Related Cognitive Impairment

Kelly Moore
Sonja Stutzman
Laurin Priddy
DaiWai Olson
CJON 2019, 23(4), 411-416 DOI: 10.1188/19.CJON.411-416
Background: Chemotherapy-related cognitive impairment refers to a cluster of symptoms commonly referred to as “chemobrain”. To date, nursing literature on the progression of and tools used to evaluate chemobrain is limited. Objectives: The purpose of this pilot study was to explore the onset of...
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Article

Chemotherapy-Induced Peripheral Neuropathy: Association With Increased Risk of Falls and Injuries

Estelle Autissier
CJON 2019, 23(4), 405-410 DOI: 10.1188/19.CJON.405-410
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and degenerative side effect of many commonly used chemotherapy agents. Symptoms manifest as sensory and motor neuropathies. CIPN may necessitate chemotherapy dose reduction or discontinuation. Objectives: This review...
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Clinical Challenges

Postchemotherapy Confusion

Sheryl L. Stewart
ONF 2001, 1361-1362 DOI:
Ms. M is a 31-year-old female with metastatic osteogenic sarcoma. She has received multiple chemotherapeutic agents in the past, including cisplatin, and has experienced periodic disease-free intervals. She has no evidence of abdominal disease and no prior nephrectomy.
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