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Dronabinol Therapy: Central Nervous System Adverse Events in Adults With Primary Brain Tumors

Deborah “Hutch” Allen
CJON 2019, 23(1), 23-26 DOI: 10.1188/19.CJON.23-26
Dronabinol is an effective adjunct to antiemetic regimens during cancer treatment in several populations of patients with cancer. However, it has been used little in central nervous system (CNS) cancers because of concerns regarding potential CNS adverse events. This secondary analysis explored CNS...
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Article

Driving and Disabling Factors of Noncurative Oral Chemotherapy Adherence: A Qualitative Evidence Synthesis

Maura Dowling
Andrew Hunter
Linda Biesty
Pauline Meskell
Aislinn Conway
Geraldine O’Boyle
Eimear Morrissey
Catherine Houghton
ONF 2019, 46(1), 16-28 DOI: 10.1188/19.ONF.16-28
Problem Identification: Adherence to oral chemotherapy is influenced by many factors. This qualitative evidence synthesis aimed to contribute to an interpretive understanding of the factors that act as facilitators or barriers to adherence among people with cancer taking lifelong, noncurative oral...
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Essentials

Vincristine Minibag Administration: A Quality Improvement Project to Minimize Medical Errors

Clara Beaver
CJON 2018, 22(6), 669-672 DOI: 10.1188/18.CJON.669-672
Vincristine is a cytotoxic chemotherapy agent classified as an antitumor alkaloid and is part of the vinca alkaloid family. Vincristine’s mechanism of action is to primarily inhibit mitosis of the cancer cell and is given by IV route only for treatment. Accidental intrathecal administration of...
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Article

5-Fluorouracil and Capecitabine: Assessment and Treatment of Uncommon Early-Onset Severe Toxicities Associated With Administration

Edith Brutcher
Deb Christensen
Melissa Hennessey Smith
Judy B. Koutlas
Jean B. Sellers
Tahitia Timmons
Joanna Thompson
CJON 2018, 22(6), 627-634 DOI: 10.1188/18.CJON.627-634
Background: Uncommon early-onset severe toxicities from 5-fluorouracil (5-FU) and capecitabine can be fatal if early warning signs are not recognized and treated promptly. Objectives: This article delineates the differences between expected side effects and uncommon early-onset severe toxicities...
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Online Exclusive Article

Food Safety Knowledge and Self-Reported Food-Handling Practices in Cancer Treatment

Ellen W. Evans
Elizabeth C. Redmond
ONF 2018, 45(5), E98-E110 DOI: 10.1188/18.ONF.E98-E110
Objectives: To explore awareness of foodborne infection risk during chemotherapy treatment, to assess knowledge of risk-reducing food safety practices in patients with cancer and their family caregivers, and to determine self-reported food-handling practices. Sample & Setting: A convenience...
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