Therapeutic misconceptions and misestimations occur frequently in oncology clinical trials and can potentially compromise informed consent. Despite the increased awareness of these issues in medical literature, many practitioners and nurses continue to be unfamiliar with these concepts. This...

Altruism often is expressed by patients with advanced cancer as a coping mechanism and a motivational factor for participation in clinical trials. Those who participate develop a sense of hope that their life is a contribution, which may continue to live beyond their deaths.

I read "Validating the Clinical Research Nursing Domain of Practice" by Castro et al. (2011) with great attention. Oncology has long recognized clinical trials as an area of specialization for nursing (Hubbard & DeVita, 1976). What began as a role in administering investigational chemotherapy...

Purpose/Objectives: To describe factors and outcomes related to the decision-making process regarding participation in a cancer clinical trial. Design: Cross-sectional, descriptive. Setting: Urban, academic, National Cancer Institute-designated comprehensive cancer center in the mid-Atlantic United...