Purpose/Objectives: To describe the roles and responsibilities of the clinical research nurse (CRN). Design: A descriptive design was used to reveal the roles of pediatric oncology CRNs. Setting: The Children's Oncology Group (COG) passwordprotected Web site. Sample: 85 nurses who performed...

Purpose/Objectives: To reveal the decision-making process in patients considering participation in cancer phase I clinical trials. Design: Grounded theory approach. Setting: Cancer center in a metropolitan area of Tokyo, Japan. Participants: 25 patients with cancer, including individuals who...

In the arena of clinical trials, patient safety is of the highest concern. Despite rules and regulations to protect participants, errors still occur. Deviations from standard practice, complexity, and unfamiliarity all may contribute to errors that occur in the research setting. Detailed and...