Purpose/Objectives: To examine relationships between capacity to direct attention and the quality-of-life (QOL) domains of psychological and physical well-being in breast cancer survivors. Design: Descriptive, correlational. Setting: National Cancer Institute-designated oncology and county hospital...

Purpose/Objectives: To explore the use of the Theory of Unpleasant Symptoms (TUS) as a model for describing the symptom experience related to the cognitive impairment associated with standard-dose chemotherapy and compare and contrast that use of the TUS with the Conceptual Model of Chemotherapy-...

Purpose/Objectives: To review the effects of chemotherapeutic agents on the blood-brain barrier as related to cytokine release and cognitive impairment. Data Sources: PubMed database. Data Synthesis: The recent findings that standard doses of chemotherapy agents reach higher than expected levels in...

Purpose/Objectives: To develop a conceptual model of chemotherapy-related changes in cognitive function. Data Sources: MEDLINE®, CINAHL®, HealthStar, and PsycINFO® databases. Data Synthesis: Patients undergoing chemotherapy often complain of forgetfulness, absentmindedness, and an inability to...