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Cognitive Impairment

Article

Neurotoxicology of Chemotherapy in Relation to Cytokine Release, the Blood-Brain Barrier, and Cognitive Impairment

Jamie S. Myers
Janet Pierce
Thomas Pazdernik
ONF 2008, 35(6), 916-920 DOI: 10.1188/08.ONF.916-920
Purpose/Objectives: To review the effects of chemotherapeutic agents on the blood-brain barrier as related to cytokine release and cognitive impairment. Data Sources: PubMed database. Data Synthesis: The recent findings that standard doses of chemotherapy agents reach higher than expected levels in...
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Article

A Meta-Analysis of the Sensitivity of Various Neuropsychological Tests Used to Detect Chemotherapy-Induced Cognitive Impairment in Patients With Breast Cancer

Catherine E. Jansen
Christine A. Miaskowski
Marilyn J. Dodd
Glenna A. Dowling
ONF 2007, 34(5), 997-1005 DOI: 10.1188/07.ONF.997-1005
Purpose/Objectives: To identify which neuropsychological tests have been used to evaluate chemotherapy-induced impairment in various domains of cognitive function in patients with breast cancer and to determine the sensitivity of each of the tests through estimation of effect size. Data Sources:...
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Article

Chemotherapy-Related Change in Cognitive Function: A Conceptual Model

Lisa M. Hess
Kathleen C. Insel
ONF 2007, 34(5), 981-994 DOI: 10.1188/07.ONF.981-994
Purpose/Objectives: To develop a conceptual model of chemotherapy-related changes in cognitive function. Data Sources: MEDLINE®, CINAHL®, HealthStar, and PsycINFO® databases. Data Synthesis: Patients undergoing chemotherapy often complain of forgetfulness, absentmindedness, and an inability to...
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Article

The Impact of Chemotherapy-Induced Cognitive Impairment on the Psychosocial Adjustment of Patients With Nonmetastatic Colorectal Cancer

Jacqueline Galica
Dale Rajacich
Debbie Kane
Gregory R. Pond
CJON 2012, 16(2), 163-169 DOI: 10.1188/12.CJON.163-169
Colorectal cancer is the third most commonly diagnosed cancer in Canada. Chemotherapy often is used as treatment for colorectal cancer, and studies have documented cognitive changes in patients after chemotherapy treatment. What remains unclear is the impact of such changes on a person's roles and...
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Supportive Care

Assessment and Management of Delirium in the Older Adult With Cancer

Susan Derby
CJON 2011, 15(3), 247-250 DOI: 10.1188/11.CJON.247-250
Recognizing delirium and its impact on older patients and their caregivers is an important aspect of oncology nursing. Delirium is the most common complication of hospital admissions for older adults and is associated with a significant amount of morbidity and mortality, prolonged hospital stays,...
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