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Genetics and Genomics

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Evaluation of Nurses and Genetic Counselors as Providers of Education About Breast Cancer Susceptibility Testing

Barbara A. Bernhardt
Gail Geller
Teresa Doksum
Sharon A. Metz
ONF 2000, 27(1), 33-39 DOI:
Purpose/Objectives: To compare outcomes of pretest education about breast cancer susceptibility testing provided by nurses and genetic counselors. Design: Two-group, post-test only evaluation of an educational intervention. Setting: A tertiary care hospital. Sample: 87 women who had a first-degree...
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Genetics & Genomics

Breast Cancer Prognostic Tests: Helping Patients Understand Testing Results and Their Implications

Lisa R. Miller
Edith Caroline Smith
CJON 2019, 23(5), 478-481 DOI: 10.1188/19.CJON.478-481
Breast cancer prognostic tests have become an essential component of breast cancer care. Oncology nurses play an important role in assisting patients in their understanding of and decision making regarding the use of prognostic tests in treatment planning. This article outlines the most commonly...
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Genetics & Genomics

Predictive Biomarkers: Understanding Their Use in Treatment Decision Making

Cyndy Simonson
CJON 2019, 23(4), 360-363 DOI: 10.1188/19.CJON.360-363
Predictive biomarkers are revolutionizing decisions about colon cancer treatment. Knowing which biomarkers are altered provides valuable information about which treatment may be more effective. DNA mismatch repair and microsatellite instability testing may also identify families that could benefit...
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Article

GATA2 Deficiency: Early Identification for Improved Clinical Outcomes

Kristen Cole
Daniele N. Avila
Mark Parta
Bazetta Blacklock Schuver
Steven M. Holland
Nirali Shah
Dennis Hickstein
CJON 2019, 23(4), 417-422 DOI: 10.1188/19.CJON.417-422
Background: Patients with GATA2 deficiency present with nontuberculous mycobacterial infections, severe viral infections (particularly refractory human papillomavirus disease), lymphedema, myelodysplastic syndrome (MDS), and acute myeloid leukemia. Patients with GATA2 deficiency who undergo...
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Genetics & Genomics

Breast Cancer Risk Prediction Models: Challenges in Clinical Application

Melissa Paquin
Tracy Fasolino
Mary Beth Steck
CJON 2019, 23(3), 256-259 DOI: 10.1188/19.CJON.256-259
Various breast cancer risk prediction models (BCRPMs) exist to assess an individual’s risk of developing malignancy and risk of having a mutation associated with hereditary risk of developing cancer. This article provides oncology nurses with current information on the available BCRPMs and...
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