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Genetics and Genomics

CNE Article

Genetic Service Delivery Models: Exploring Approaches to Care for Families With Hereditary Cancer Risk

Jennifer M. Pierle
Suzanne M. Mahon
CJON 2019, 23(1), 60-67 DOI: 10.1188/19.CJON.60-67
Background: Providing timely access to quality genetic counseling is becoming necessary as the awareness and availability of high-risk screening and genetic testing increase. The results of genetic testing directly influence treatment decisions and recommendations for cancer screening and...
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Genetics & Genomics

Metastatic Prostate Cancer: Effects of Genetic Testing on Care

Laurie M. Connors
CJON 2019, 23(1), 32-35 DOI: 10.1188/19.CJON.32-35
The National Comprehensive Cancer Network now recommends BRCA1/2 genetic testing in men with metastatic prostate cancer. The purpose of this article is to provide a review of principles of genetic testing in prostate cancer and highlight the significance of clinical genetic testing of BRCA1/2 and...
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Letter to the Editor

Response to "Male Patients With Breast Cancer: Addressing Needs Using an Educational Task Force"

Suzanne M. Mahon
Joaimee Nagtalon Cutrone
Roberta H. Baron
CJON 2018, 22(6), 610 DOI: 10.1188/18.CJON.610
Male breast cancer is associated with hereditary risk for developing breast and other cancers. An estimated 4% of men with breast cancer have BRCA1 mutations, and 4%-16% have BRCA2 mutations. Men with a diagnosis of breast cancer have unique needs that need to be addressed in a caring and...
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Genetics & Genomics

Cancer-Related Pain: Understanding Genetic Influences and Determining Implications for Practice

Karen Jakub
CJON 2018, 22(6), 607-609 DOI: 10.1188/18.CJON.607-609
Pain can be highly variable and unpredictable. Genetics may be key to identifying pain mechanisms that control the intensity, duration, and physiologic response in individuals with chronic pain. Pharmaco-genomics and precision medicine are permitting advances in pain control with analgesic drugs...
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Online Exclusive Article

Symptoms and Health-Related Quality of Life in Patients Receiving Cancer Therapy Matched to Genomic Profiles

Kirstin Williams
Sandra Bergquist-Beringer
ONF 2018, 45(6), E125-E136 DOI: 10.1188/18.ONF.E125-E136
Objectives: To examine symptom occurrence and severity and overall health-related quality of life (HRQOL) in patients receiving cancer therapy guided by genomic profiling (matched therapy) and patients receiving nonmatched therapy. Sample & Setting: A retrospective and secondary analysis of...
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