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Genetics and Genomics

Genetics & Genomics

Predictive Biomarkers: Understanding Their Use in Treatment Decision Making

Cyndy Simonson
CJON 2019, 23(4), 360-363 DOI: 10.1188/19.CJON.360-363
Predictive biomarkers are revolutionizing decisions about colon cancer treatment. Knowing which biomarkers are altered provides valuable information about which treatment may be more effective. DNA mismatch repair and microsatellite instability testing may also identify families that could benefit...
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Article

GATA2 Deficiency: Early Identification for Improved Clinical Outcomes

Kristen Cole
Daniele N. Avila
Mark Parta
Bazetta Blacklock Schuver
Steven M. Holland
Nirali Shah
Dennis Hickstein
CJON 2019, 23(4), 417-422 DOI: 10.1188/19.CJON.417-422
Background: Patients with GATA2 deficiency present with nontuberculous mycobacterial infections, severe viral infections (particularly refractory human papillomavirus disease), lymphedema, myelodysplastic syndrome (MDS), and acute myeloid leukemia. Patients with GATA2 deficiency who undergo...
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Genetics & Genomics

Breast Cancer Risk Prediction Models: Challenges in Clinical Application

Melissa Paquin
Tracy Fasolino
Mary Beth Steck
CJON 2019, 23(3), 256-259 DOI: 10.1188/19.CJON.256-259
Various breast cancer risk prediction models (BCRPMs) exist to assess an individual’s risk of developing malignancy and risk of having a mutation associated with hereditary risk of developing cancer. This article provides oncology nurses with current information on the available BCRPMs and...
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Letter to the Editor

Response to “Workplace Wellness Programs: Educating Patients and Families About Discrimination Via Disclosure of Genetic Information”

Mary Beth Steck
CJON 2019, 23(2), 124 DOI: 10.1188/19.CJON.124
An article by Steck (2018), published in the August issue of the Clinical Journal of Oncology Nursing , stated that workplace wellness programs are legally permitted to request the family medical history of employees. However, since publication, the previously cited regulations have been redacted,...
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Genetics & Genomics

Flipped Classroom Strategy: An Accessible, Application-Driven Approach to Genomics Education

Kelliann C. Fee-Schroeder
Dawn M. Nelson
CJON 2019, 23(2), 145-148 DOI: 10.1188/19.CJON.145-148
Gaps in nurses’ knowledge and application related to genomics exist. This project aimed to develop an accessible genomic education program for oncology nurses. Consequently, the flipped classroom strategy was used. This involved the use of prework consisting of an online genetics and genomics...
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