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CNE Article
CJON Writing Mentorship Article

Atypical Hemolytic Uremic Syndrome: Achieving Positive Patient Outcomes With Early Diagnosis and Appropriate Management

Dmitriy Sverdlin
Brenda Peters-Watral
CJON 2017, 21(4), 481-487 DOI: 10.1188/17.CJON.481-487
Background: Atypical hemolytic uremic syndrome (aHUS), a condition found in adult and pediatric populations, can be idiopathic or acquired as a result of major systemic changes. aHUS presents with a wide array of symptoms that can be attributed to other less dangerous conditions. Because of its...
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Online Exclusive Article

High-Dose Interleukin-2: Evaluation of a Standardized Order Set for Biotherapy in an Intensive Care Unit

Rusticio Portillas
Barbara Turner
Audrey Jeffers
Lee-Lynn Chen
Mary Champagne
CJON 2017, 21(2), E49-E53 DOI: 10.1188/17.CJON.E49-E53
Background: Life-threatening toxicity may result from administration of high-dose (HD) interleukin-2 (IL-2). Patients receiving HD IL-2 treatment often experience severe adverse side effects, which result in the interruption of treatment. Objectives: A standardized order set (SOS) was developed for...
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Article

Optimizing Patient Adherence to Targeted Therapies in Renal Cell Carcinoma: Practical Management Strategies in the Second-Line Setting

Patricia A. Creel
CJON 2014, 18(6), 694-700 DOI: 10.1188/14.CJON.694-700
The current standard of care for treating metastatic renal cell carcinoma is sequential therapy with vascular endothelial growth factor-targeted agents (i.e., axitinib, bevacizumab, pazopanib, sorafenib, and sunitinib) and mammalian target of rapamycin inhibitors (i.e., everolimus and temsirolimus...
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Clinical Challenges

Noninfectious Pneumonitis in a Patient With Renal Cell Carcinoma Treated With Everolimus

Patricia Creel
Nancy P. Moldawer
ONF 2011, 38(2), 125-128 DOI: 10.1188/11.ONF.125-128
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Article

Renal Complications in Multiple Myeloma and Related Disorders

Beth M. Faiman
Patricia Mangan
Jacy Spong
Joseph D. Tariman
the International Myeloma Foundation Nurse Leadership Board
CJON 2011, 15(4), 66-76 DOI: 10.1188/11.CJON.S1.66-76
Kidney dysfunction is a common clinical feature of symptomatic multiple myeloma. Some degree of renal insufficiency or renal failure is present at diagnosis or will occur during the course of the disease and, if not reversed, will adversely affect overall survival and quality of life. Chronic...
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