The Bridge From Genomic Discoveries to Disease Prevention

American Cancer Society. (2006). Cancer facts and figures 2006. Atlanta, GA: Author.

Antoniou, A.C., & Easton, D.F. (2006). Risk prediction models for familial breast cancer. Future Oncology, 2, 257-274.

Baak, J.P., Path, F.R., Hermsen, M.A., Meijer, G., Schmidt, J., & Janssen, E.A. (2003). Genomics and proteomics in cancer. European Journal of Cancer, 39, 1199-1215.

Baglietto, L., Jenkins, M.A., Severi, G., Giles, G.G., Bishop, D.T., Boyle, P., et al. (2006). Measures of familial aggregation depend on definition of family history: Meta-analysis for colorectal cancer. Journal of Clinical Epidemiology, 59, 114-124.

Barse, P.M. (2003). How to perform a genetic assessment. In A.S. Tranin, A. Masny, & J. Jenkins (Eds.), Genetics in oncology practice: Cancer risk assessment (pp. 57-76). Pittsburgh, PA: Oncology Nursing Society.

Bennett, R.L. (1999). The practical guide to the genetic family history. New York: John Wiley.

Cannistra, S.A. (1997). "Cancer defeated": Not if, but when—Introducing the Biology of Neoplasia series. Journal of Clinical Oncology, 15, 3297-3298.

Chen, S., Iversen, E.S., Friebel, T., Finkelstein, D., Weber, B.L., Eisen, A., et al. (2006). Characterization of BRCA1 and BRCA2 mutations in a large United States sample. Journal of Clinical Oncology, 24, 863-871.

Collins, F.S. (1999). Shattuck lecture: Medical and societal consequences of the Human Genome Project. New England Journal of Medicine, 341, 28-37.

Dolan DNA Learning Center, Cold Spring Harbor Lab. (2006). Inside cancer: Hallmarks of cancer. Retrieved February 10, 2006, from http://www.insidecancer.org

Dove-Edwin, I., Sasieni, P., Adams, J., & Tomas, H.W. (2005). Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16-year prospective follow-up study. BMJ, 331, 1047-1053.

Fearon, E.R. (1997). Human cancer syndromes: Clues to the origin and nature of cancer. Science, 278, 1043-1050.

Frank, T.S., Deffenbaugh, A.M., Reid, J.E., Hulick, M., Ward, B.E., Lingenfelter, B., et al. (2002). Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: Analysis of 10,000 individuals. Journal of Clinical Oncology, 20, 1480-1490.

Garber, J.E., & Offit, K. (2005). Hereditary cancer predisposition syndromes. Journal of Clinical Oncology, 23, 276-292.

Genetics Home Reference. (2006). Search results: Cancer and genes. Retrieved March 24, 2006, from http://ghr.nlm.nih.gov/ghr/search?query=cancer+and+genes

Kennedy, J.F. (1963). Remarks at the dedication of the Aerospace Medical Health Center, San Antonio, TX, November 21. Retrieved February 10, 2006, from http://www.jfklibrary.org/Historical+Resources/Archives/Reference+Desk/Speeches/JFK/003POF03AerospaceMedicalCenter11211963.htm

Kinzler, K.W., & Vogelstein, B. (1997). Gatekeepers and caretakers. Nature, 386, 761, 763.

Knudson, A.G. (2002). Cancer genetics. American Journal of Medical Genetics, 111, 96-102.

Lindor, N.M., & Greene, M.H. (1998). The concise handbook of family cancer syndromes. Journal of the National Cancer Institute, 90, 1039-1071.

Lynch, H.T., Shaw, T.G., & Lynch, J.F. (2004). Inherited predisposition to cancer: A historical overview. American Journal of Medical Genetics, Part C. Seminars in Medical Genetics, 129, 5-22.

Lynch, H.T., Snyder, C.L., Lynch, J.F., Riley, B.D., & Rubinstein, W.S. (2003). Hereditary breast-ovarian cancer at the bedside: Role of the medical oncologist. Journal of Clinical Oncology, 21, 740-753.

Lynch, H.T., Tinley, S.T., Lynch, J.F., & Attard, T.M. (2004). Challenging pedigrees seen in a hereditary cancer consultation center. Cancer Genetics and Cytogenetics, 153, 91-101.

Mahon, S.M. (2003). Cancer-risk assessment: Considerations for cancer genetics. In A.S. Tranin, A. Masny, & J. Jenkins (Eds.), Genetics in oncology practice: Cancer risk assessment (pp. 77-138). Pittsburgh, PA: Oncology Nursing Society.

McPherson, J.D., Marra, M., Hillier, L., Waterston, R.H., Chinwalla, A., Wallis, J., et al. (2001). A physical map of the human genome. Nature, 409, 934-941.

Merg, A., Lynch, H.T., Lynch, J.F., & Howe, J.R. (2005). Hereditary colon cancer, Part 1. Current Problems in Surgery, 42, 195-256.

Metcalfe, K., Lynch, H.T., Ghadirian, P., Tung, N., Olivotto, I., Warner, E., et al. (2004). Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. Journal of Clinical Oncology, 22, 2328-2335.

National Comprehensive Cancer Network. (2006). NCCN clinical practice guidelines in oncology: Guidelines for the detection, prevention, and risk reduction of cancer. Jenkintown, PA: Author.

Perera, F.P. (1997). Environment and cancer: Who are susceptible? Science, 278, 1068-1073.

Regalado, A. (2002, January 11). The great gene grab: Will the frenzy of gene patenting drive innovation—or stifle medical advances? Technology Review. Retrieved January 6, 2006, from http://www.technologyreview.com/read_article.aspx?id=12184

Ricciardiello, L., & Boland, C.R. (2005). Lynch syndrome (hereditary nonpolyposis colorectal cancer): Current concepts and approaches to management. Current Gastroenterology Reports, 7, 412-420.

Ruddon, R.W. (1995). Cancer biology (3rd ed.). New York: Oxford University Press.

Sellick, G.S., Catovsky, D., & Houlston, R.S. (2006). Familial chronic lymphocytic leukemia. Seminars in Oncology, 33, 195-201.

Shields, P.G., & Harris, C.C. (2000). Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. Journal of Clinical Oncology, 18, 2309-2315.

Simpson, A.J. (1997). The natural somatic mutation frequency and human carcinogenesis. Advances in Cancer Research, 71, 209-240.

Varmus, H. (2006). The new era in cancer research. Science, 312, 1162-1165.

Venter, J.C., Adams, M.D., Myers, E.W., Li, P.W., Mural, R.J., Sutton, G.G., et al. (2001). The sequence of the human genome. Science, 291, 1304-1351.

Vogelstein, B., & Kinzler, K.W. (Eds.). (1998). The genetic basis of human cancer. New York: McGraw-Hill.

Vogelstein, B., & Kinzler, K.W. (2004). Cancer genes and the pathways they control. Nature Medicine, 10, 789-799.