EACA (Epsilon-Aminocaproic acid)

Epsilon-aminocaproic acid is a potent antifibrinolytic agent used to control bleeding by inhibiting the plasmin-plasminogen system. It can be administered orally or intravenously and is excreted in the urine. Major side effects include cardiac arrhythmias, hypotension, rhabdomyolysis, and creation of thrombi. It may be beneficial in the prevention of bleeding, but additional studies are necessary. 

Guideline / Expert Opinion