Linaclotide
Linaclotide, a peptide agonist of specific receptors in the lumen of the gastrointestinal tract, accelerates colonic transit time. This medication has been used in individuals with chronic constipation, but has not been specifically studied in patients with cancer and cancer-related constipation symptoms.
Limited Intraoperative Hydration
Limiting the volume of IV fluids during surgery was examined for its impact on intraoperative blood loss and postoperative bleeding in patients undergoing cancer surgery.
Light Therapy/Visible Light Therapy
Light therapy/visible light therapy involves exposure to light wavelengths that are in the visible spectrum. Light therapy has been studied for its effect on fatigue and oral mucositis.
Licorice
Licorice is made from the root of the Glycyrrhiza glabra plant, a legume native to southern Europe, India, and Asia. Licorice is most commonly known in its extracted form, which lends a sweet flavor to foods, coffee, or tobacco. It has been investigated as a potential treatment for oral mucositic in patients with cancer.
Levofloxacin and Cholestyramine
Levofloxacin is a fluoroquinolone antibiotic. It is used for the treatment of pneumonia, chronic bronchitis, and sinus, urinary tract, kidney, prostate, and skin infections.
LED Light
Light-emitting diodes (LEDs) are a semi-conductor light source, releasing energy in the form of photons. Exposure to LED light was studied in patients with cancer for its effect on the prevention and treatment of radiodermatitis.
Lansoprazole
Lansoprazole is a proton pump inhibitor (PPI) that inhibits gastric acid production in the stomach. The drug is available over-the-counter in the United States, and its uses include the prevention and treatment of ulcers in the stomach and duodenum; the treatment of gastroesophageal reflux disease (GERD); and the treatment of Helicobacter pylori infections in which it is used as an adjunctive therapy. The most common side effects are diarrhea and skin rashes or itching.
Lamotrigine
Lamotrigine is an anticonvulsant that inhibits the function of neuronal sodium channels, decreasing the release of excitatory neurotransmitters. Lamotrigine has been evaluated for the management of peripheral neuropathy and neuropathic pain. It is available as a tablet, extended release tablet, chewable tablet, and an orally dissolving tablet.
Lactulose
Lactulose, an osmotic laxative, contains poorly absorbed ions or molecules that create a local osmotic gradient within the intestinal lumen. Fluid and electrolytes are drawn osmotically from the surrounding tissue into the colon, which creates pressure-stimulating peristalsis. Adverse effects of lactulose include electrolyte abnormalities, diarrhea, abdominal bloating, flatulence, and colic.
Lactobacillus Lozenges
Oral lozenges containing Lactobacillus brevi were studied for effects to reduce oral mucositis in patients with cancer. This particular probiotic has anti-inflammatory properties.