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Clinical Challenges

Malakoplakia After Allogeneic Hematopoietic Stem Cell Transplantation

Tracy Robinson
Erin Streu
ONF 2015, 42(5), 558-561 DOI: 10.1188/15.ONF.558-561

A 32-year-old woman named A.C. was diagnosed five years ago with stage IIIB nodular sclerosing Hodgkin lymphoma. Following initial chemotherapy, she had refractory disease as evidenced by hypermetabolic activity on positron-emission tomography scan. A.C. was treated with a short course of salvage chemotherapy, stem cell collection, and autologous HSCT about 11 months after initial diagnosis. Her post-transplantation course was complicated by pneumonia and interstitial lung disease secondary to chemotherapy that rapidly improved with high-dose steroids.

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